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Janumet is an antidiabetic medication that contains metformin and sitagliptin. The medicine is clinically proven to control blood sugar levels for type 2 diabetics. The drug is not used for treating type 1 diabetes.

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Our pharmacy will send your treatment right to your doorstep. this service includes doctor prescription and 24h express delivery.

  • Free next day delivery
  • Prescription included
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How to buy Janumet?

Janumet is an effective treatment for type 2 diabetes and available to buy online when you get a prescription. This can be easily obtained when completing our quick consultation. A certified doctor reviews this and then you can order Janumet online.

Is it safe to order online?

When ordering from a certified online pharmacy, you can be ensured that your medication is safe. If the pharmacy doesn't ask you to complete essential health and medical question, however, this is a telltale sign that the website isn't certified. The website should also display clear signs that it is registered and approved by the relevant authorities. In the UK, this includes being registered by the MHRA, GMC .

All medication will be delivered in tamper proof packaging complete with the full patient leaflet, which confirms that the medication is clinically proven and highly effective.

What is included in the price?

When ordering Janumet online here at HEALTHSITE, this is an all-inclusive price including the prescription, consultation, medication and delivery. There are no hidden costs. The price adjusts depending on the dosage and quantity you have ordered, which can be seen below:


Can you buy without a prescription?

No. All clinically proven medication requires a valid prescription and Janumet is no exception. This is to confirm the medication is perfectly safe and highly effective for you to use. The prescription process will involve a short consultation – this is the same in person as well as online – and involves medical and personal question to ensure Janumet is compatible with you.

What is Janumet?

Janumet is an effective type 2 diabetes medication available in tablet form to be taken on a daily basis. It helps to control blood sugar levels when teamed with a healthy diet and exercise. It is available to buy online here at HEALTHSITE after you have bee diagnosed with type 2 diabetes.

How does it work?

Janumet is a combination of metformin and sitagliptin. Metformin works by decreasing the production of glucose in the livery and by decreasing its absorption by the intestines. Sitagliptin regulates the levels of insulin that the body produces after consumption of food.

How to take Janumet

Janumet should be taken exactly as prescribed. It is important to follow the exact dose and not to take either a lower or a higher dose than recommended by the doctor. Janumet is available as both an immediate release and an extended release tablet and should be taken with meals.

  • It should be swallowed completely without crushing, chewing or breaking the tablet.
  • Janumet is not the complete treatment solution for type 2 diabetes and should be accompanied with a healthy diet, exercise, foot care and eye care.

The dose of the drug is based on the patient's current condition, tolerance level and the effectiveness of the drug in controlling their blood sugar level. However, the dose should not exceed 2,000mg metformin and 100mg sitagliptin daily. The drug should ideally be taken twice daily with meals. The dose should be escalated gradually so as to reduce the risk of gastrointestinal side effects associated with metformin. The product should not split or divided before swallowing.

What if I miss a dose?

If you miss a dose, take it as soon as you remember it. Janumet must be taken with food. However, if it's almost time for the next dose, do not take the missed tablet. Double dosing is not recommended.

Dosing Guidelines

Immediate-Release tablet

  • For patients not treated with Metformin, Janumet immediate release tablet at a dose of metformin 500mg-sitagliptin 50mg taken orally twice a day.
  • For patients already treated with Metformin, Janumet immediate release tablet with sitagliptin 50mg and 500 or 1,000mg metformin twice a day taken orally.

Extended-Release Tablet

  • For patients not currently treated with metformin, the recommended dose is metformin 1,000mg-sitagliptin 100mg once a day taken orally.
  • For patients already treated with metformin, the recommended dose is sitagliptin 100mg and 500 or 1,000mg metformin once a day taken orally. For patients who are already taking metformin immediate-release 850 mg or 1,000mg twice a day, the recommended dose is two tablets of metformin 1,000mg-sitgliptin 50mg taken together once a day.

What if I overdose?

In the case of an overdose, call a medical professional immediately. Some symptoms of drug overdose may include extreme weakness, blurred vision, sweating, stomach pain, tremors, confusion, trouble speaking and convulsions.

Janumet side effects

Some common side effects of Janumet include upset stomach, gas, diarrhoea, nausea and vomiting, headache, weakness, cold symptoms such as runny nose, sneezing and a sore throat.

Some serious side effects may include severe or ongoing pain in joints, problem urinating, shortness of breath, rapid weight gain, swelling in hands or feet, severe skin reaction, skin pin, rashes, blistering or peeling, fever and burning in your eyes.

Janumet Precautions

Janumet should not be used in patients with type 1 diabetes for the treatment of diabetic ketoacidosis. Its use has also not been studied in patients with a history of pancreatitis and thus should be avoided. Treatment with Janumet should be stopped immediately in case of an allergic reaction. Symptoms would include hives, difficulty in breathing, swollen face, lips, tongue or throat.

The safety and effectiveness of Janumet has not been established in children under the age of 18 years.

Treatment should be stopped immediately as well if you see symptoms of pancreatitis which would include severe stomach pain that could spread to the back, nausea and vomiting, fast heartbeat and/or loss of appetite.

In case of lactic acidosis, stop treatment and get medical help. Symptoms could include muscle pain or weakness, breathing problem, numbness in arms and legs, dizziness, stomach pain, nausea and vomiting and irregular heart rate.

Janumet is not known to cause low blood sugar but if the drug is prescribed with other anti-diabetic medications, this may occur. In this case, the dose may have to be adjusted and it is advisable to seek medical advice in this regard.

Pregnancy and breastfeeding

Janumet should be used during pregnancy if absolutely needed. It is generally recommended that insulin is used during pregnancy instead of this product.

It is important to note that metformin can result in changes in a woman's menstrual cycle and can promote ovulation thus increasing the risk of pregnancy. Therefore, for women on birth control, it is advisable to consult their healthcare provider regarding other reliable or more effective methods of contraception while taking Janumet.

Metformin is known to pass into the breast milk though in small amounts. It is yet unknown if sitagliptin passes into breast milk. Therefore it is best to consult your doctor before breast-feeding if you're on Janumet.

Drug Interactions

You should always inform your doctor about all prescription/non-prescription drugs and herbal products that you use. The following medicines have been found to interact with Janumet:

  • Beta-blocker medications such as metoprolol, propranolol, and glaucoma eye drops such as timolol as they can affect blood sugar levels and may make it difficult to control it.

Serious interactions have been observed with:

  • Antidiabetic agents Gymnema and Gatifloxacin

Moderate interactions have been observed with:

  • Selected Quinolones
  • Metformin/Cimetidine
  • Metformin/Cephalexin
  • Metformin/Ranolazine
  • Metformin/Carbonic Anhydrase Inhibitors
  • Metformin/Dolutegravir
  • Metformin/Trimethoprim
  • Hypoglycaemic; Insulin/Bupropion

Certain drugs tend to produce hyperglycaemia and may lead to loss of glycemic control. These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. Caution should be exercised while using Janumet with these drugs.


Janumet is contraindicated in patients with:

  • Renal Impairment
  • Hypersensitivity to Metformin Hydrochloride
  • Acute or Chronic Metabolic Acidosis Including Diabetic Ketoacidosis
  • History of Hypersensitivity to Janumet or Sitagliptin
This is how we work
  • Select your medication

    Choose the medication you would like to order and select the appropriate dosage and quantity to proceed with your consultation.

  • Complete a private medical form

    Complete your medical consultation form which provides your online doctor with further information about your condition.

  • Doctor issues prescription

    Online doctor checks your medical form, a prescription is created and sent directly to our pharmacy who will then dispatch your medication.

  • Medication delivered the very next day

    Our registered UK pharmacy will complete a final dispatch check ensuring you receive the right treatment the following day.

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3h 38min for delivery tomorrow