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Home / Erectile Dysfunction / Spedra


  • Pack of 4 Spedra 200mg avanafil oral tablets
  • Box of Spedra 200mg tablets with a blister strip
  • Front view of Spedra tablet blister pack

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Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

How to buy Spedra

Spedra is available from your local pharmacy after attending a doctor's appointment to retrieve a prescription. Alternatively, you can buy Spedra tablets here at Medilico after completing a confidential online consultation. Our UK registered doctors will review this consultation before providing you with an official prescription for this medication. You will then be able to successfully place your order. Ensure you mention any current medications you take or any conditions you are currently experiencing. It is not possible to buy Spedra or any other erectile dysfunction medications over-the-counter.

Is it safe to order online?

When ordering from a certified online pharmacy, you can be ensured that your medication is safe. If the pharmacy doesn't ask you to complete essential health and medical question, however, this is a telltale sign that the website isn't certified. The website should also display clear signs that it is registered and approved by the relevant authorities. In the UK, this includes being registered by the MHRA and GMC.

All medication will be delivered in tamper proof packaging complete with the full patient leaflet, which confirms that the medication is clinically proven and highly effective.

What is included in the price?

When you buy Spedra tablets online here at Medilico, this is an all-inclusive price including the prescription, consultation, medication and delivery. There aren't any hidden costs. The price of this medication adjusts according to the dosage and quantity you have ordered, which can be seen below:

Can you buy without a prescription?

No. All clinically proven medications will require a valid prescription and Spedra is no different. To obtain Spedra you'll require a prescription from a registered doctor. A prescription will confirm that this medication is perfectly suitable and highly effective for you to use. The prescription process itself will include a quick online consultation, which is the same in person as well as online and involves medical and personal questions, ensuring this treatment is compatible with you.

What is Spedra?

Spedra is a relatively new medication used for the successful treatment of erectile dysfunction. Spedra contains the active ingredient called avanafil, which has been shown to increase blood flow to the penis. This increased blood flow results in a prolonged erection. Spedra is available to buy online with a prescription for men who have erectile dysfunction. It works much faster than many other similar drugs in the market for this problem. Most men achieve a sustained erection within 20 minutes after swallowing the tablet. Spedra is in the same class of drugs as Viagra, Cialis and Levitra. Spedra does not spontaneously cause erection of the penis. One has to be sexually aroused first.

How effective is Spedra?

It is important to remember that Spedra does not cure erectile dysfunction. However, the drug may help boost self-esteem and confidence in social circles and personal relationships. It does this by improving your sex life.

Spedra has been studied in clinical trials and has been shown to be more effective than a sugar pill (placebo). Unlike other similar drugs on the market for erectile dysfunction, the biggest advantage of spedra is that it has a very fast onset of action. Spedra is absorbed very quickly from the empty stomach reaching peak concentration in the blood within 30-45 minutes. Most people in the clinical trials were able to engage in satisfactory sexual intercourse within 15 minutes.

In some men, Spedra may not work the first time. Experts recommend that you try the medication several times before having your dose adjusted or having the medication discontinued.

Experts recommend that diabetics who have difficulties with erections can try Spedra. Anecdotal reports indicate that Spedra does help achieve satisfactory erections in some diabetics.

Many antipsychotic and antidepressant drugs suppress libido. In these people, lowering or discontinuing the drug is not an option. Experts recommend that Spedra may be an option for some people who have the inability to achieve an erection after taking antidepressants.

What is Spedra used for?

Spedra is used to treat men who have erectile dysfunction (impotence). There are men who are unable to achieve a sufficient erection for penetration. Spedra only works for men who have difficulty achieving an erection as a result of stress or emotional conflicts. It does not work for men who have an organic cause of impotence. For example, if you have had an injury in penile area Spedra will not help you achieve an erection. It is important to note that Spedra is not an aphrodisiac, it only enables one to have an erection for satisfactory sexual intercourse.

How does Spedra work?

Spedra is classified as a phosphodiesterase 5-inhibitor. It acts by inhibiting the phosphodiesterase enzyme in the penile tissues which results in the generation of nitric oxide. Nitric oxide is known to open up blood vessels resulting in increased blood flow to the penis. The end result is a sustained erection.

How to take Spedra?

Spedra should be taken about 15-30 minutes prior to anticipated sexual intercourse. Once the pill is ingested, some form of manual stimulation is needed to arouse the penis. Once the penis is erect, it will remain rigid and stiff for vaginal penetration. Spedra is best taken on an empty stomach. But if you develop nausea, it can be taken with a meal. It is important to avoid taking Spedra with a fatty meal, as this delays its absorption from the digestive tract.

Spedra dosages

Spedra is available in 3 formulations, 50mg, 100mg, and 200mg tablets. Most people start on the low dose pill and then titrate upwards until they see a response. One should not take more than one pill of Spedra a day.

Once Spedra is taken, an erection will develop within 15-20 minutes and last for 4-6 hours or longer.

The chief reason for the different dosages of Spedra is that some men who take other medications (e.g. blood pressure medications) may require a lower dose. The dose of Spedra depends on your age, use of other medications and severity of erectile dysfunction.

Spedra Side Effects

Like all medicines Spedra can have side effects, including headaches, which are often mild, but can persist during sex and for a few hours after the sexual activity. Side effects can also include facial flushing (within 20 minutes of taking the pill) or nasal congestion soon after ingestion.

Some uncommon side effects may include dizziness, sinus headaches, blurred vision, hot flushes, sinus congestion, dyspnoea exertional, dyspepsia, nausea, vomiting, stomach discomfort, back pain, muscle tightness, fatigue, an increase in hepatic enzyme, abnormal ECG or an increased heart rate.

Rare side effects can possibly include insomnia, premature ejaculation, psychomotor hyperactivity, angina pectoris, tachycardia, hypertension, rhinorrhoea, upper respiratory tract congestion, dry mouth, gastritis, lower abdominal pain, diarrhoea, a rash, flank pain, myalgia, muscle spasms, pollakiuria, spontaneous penile erection, asthenia, chest pain, weight gain or increased blood pressure.

Spedra Precautions

Spedra tablets should not be used by the following:

  • Men under the age of 18.
  • Men who have allergy to avanafil or to anyone the ingredients in Spedra.
  • Men who are taking nitrite medication for their heart disease.
  • Men who are taking medications for HIV or a fungal infection.
  • Men who have a heart disease or have had a heart attack.
  • Spedra should not be used by men with moderate to severe liver problems.
  • The drug should also not be used by men who have certain inherited disorders of the eye.
  • Anyone who has had a stroke should avoid Spedra.
  • The drug is not to be used by women.

The following precautions should also be followed when taking Spedra tablets:

  • It is not recommend that you drive immediately after you take Spedra because the medication can potentially cause dizziness, fatigue or blurred vision.
  • Avoid use of heavy machinery while taking Spedra.
  • Spedra can slightly lower the blood pressure, but this is not of clinical significance in most healthy adults who do not take any other medications. However, people who take nitrite or other blood pressure medications may have a moderate drop in their blood pressure. One should never take nitrates and Spedra at the same time.
  • If you have any type of heart disease, you should first speak to your doctor before you take Spedra. The drug can interact with nitrites, which are used for treatment of angina.
  • Do not take Spedra with grapefruit juice within 24 hours.
  • Avoid taking Spedra with alcohol as this may result in lowering of blood pressure and an increase in heart rate. Furthermore, alcohol may prevent Spedra from causing an erection.

Other medication Interactions

Spedra can interact with several medications. Therefore, before you take the medication you should speak to your doctor and tell him/her about all medications, herbs and supplements that you are currently taking. It is very important that you not combine Spedra with Viagra, Cialis or Levitra. The potential for adverse reactions and toxicity is increased.

Other drugs known to interact negatively with Spedra include the following:

  • Nitrate medications
  • Nitroprusside
  • Cimetidine
  • Erythromycin
  • Azole antifungals
  • Mibefradil
  • Rifamycins
  • Alpha blockers, prescribed for prostate disease or high blood pressure
  • Ritonavir, Amyl, Butyl or Isopropyl nitrates
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