Phone Live Chat
Customer Service Team available now: Mon-Fri 8:00-17:00
  • Private & confidential service
  • Genuine medication
  • All-inclusive service - No hidden fees
  • Next day delivery
Home / HRT / Elleste


  • Elleste Solo and Elleste Duet tablets
  • Pack of 84 Elleste Solo 1mg estradiol hemihydrate tablets with blister packs
  • Pack of 84 Elleste Duet 1mg with blister packs (each containing 16 tablets of 1mg estradiol hemihydrate and 12 tablets of 1mg estradiol hemihydrate/1mg norethisterone acetate)

COVID-19 update: Our services are running as normal.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

How to buy Elleste?

You can order Elleste online once your doctor has prescribed it for you. This is to ensure your safety. Elleste Solo, Elleste Solo MX, Elleste Duet and Elleste Duet Conti can interact with medicines and are not suitable for some medical conditions and lifestyles. If your doctor does not prescribe you HRT speak about alternative options and natural methods to help support you through menopause.

Is it safe to order online?

When ordering from a certified online pharmacy, you can be ensured that your medication is safe. If the pharmacy doesn't ask you to complete essential health and medical question, however, this is a telltale sign that the website isn't certified. The website should also display clear signs that it is registered and approved by the relevant authorities. In the UK, this includes being registered by the MHRA, GMC .

All medication will be delivered in tamper proof packaging complete with the full patient leaflet, which confirms that the medication is clinically proven and highly effective.

What is included in the price?

When ordering Elleste online here at Medilico, this is an all-inclusive price including the prescription, consultation, medication and delivery. There are no hidden costs. The price adjusts depending on the dosage and quantity you have ordered.

Can you buy without a prescription?

Hormone replacement therapy (HRT) is a prescription-only treatment. It's not possible to buy it over-the-counter. This is to confirm the medication is perfectly safe and highly effective for you to use. The prescription process will involve a short consultation – this is the same in person as well as online – and involves medical and personal question to ensure Azithromycin is compatible with you. For STI medications, you must have tested positive before taking the treatment.

What is Elleste?

Elleste is a tablet or patch that replaces the hormones lost during your menopause.

When women reach menopause they can experience difficult to live with symptoms including hot flashes, night sweats and osteoporosis. Elleste minimises these symptoms by replacing the lost hormones. Elleste is available in three different versions to suit your health and personal needs. They are:

  • Elleste Solo: An oestrogen only HRT which contains estradiol hemihydrate. This is a natural form of oestrogen and is only suitable for women who no longer have a uterus.
  • Elleste Solo MX: A transdermal patch version of Elleste Solo. You can swim, shower and bathe wearing the patch.
  • Elleste Duet: A combined HRT that contains both the oestrogen estradiol hemihydrate and the progesterone norethisterone acetate. Elleste Duet is available in two different strengths and is available for women who still have their uterus.
  • Elleste Duet Conti: A combined HRT that contain both the oestrogen estradiol hemihydrate and the synthetic progesterone norethisterone acetate. Elleste Duet Conti is also available in two different strengths for women who still have a uterus. Elleste Duet Conti has the same ingredients and works the same way as Elleste Duet, but is delivered in different doses.

How Does Elleste Work?

Menopause means the end of a woman's fertile time. When women approach menopause the ovaries stop releasing eggs and cut down on the amount of hormones that are produced. This can lead to a variety of symptoms that are both distressing. This includes hot sweats, mood swings and hot flashes and lesser known symptoms such as a dry vagina. Not all women need the support of HRT but in cases where menopause is interfering with everyday life Elleste can help.

Women who still have their uterus need a combined HRT such as Elleste Duet or Elleste Duet Conti because progesterone is needed to counteract the oestrogen produced by your ovaries. Too much oestrogen can lead to ill health.

Elleste also reduces the risk of osteoporosis. Osteoporosis is when bones lose their mass and become prone to breaking. In very severe cases bones can break simply by coughing or laughing. Osteoporosis is a risk during menopause because oestrogen builds strong bones. When women don't produce oestrogen any longer their bones cannot build themselves into strong supports. Elleste replaces the missing oestrogen and helps to build strong bones.

How To Use Elleste

Elleste is suitable for women who have tried natural ways to relieve their menopausal symptoms without success.

If natural methods do not work, HRT such as Elleste can be taken at the lowest dose you need for the shortest time period. Your doctor will decide which HRT is suitable for you, but if you find that the dose is not strong enough there are higher doses of Elleste Solo, Elleste Duet or Elleste Duet Conti available.

  • All Elleste HRT tablets should be taken once a day at suitable time
  • Try to ensure you take your tablet at the same time each day to create an even spread of hormone delivery that minimises side effects and maximises the hormonal benefit
  • Swallow tablets whole with water. Do not crush or chew your tablets

All Elleste tablets are taken once a day, and when you finish your pack you should start a new one straight away.

Elleste in all three forms consist of a daily tablet. Elleste Solo is also available as a transdermal patch called Elleste Solo MX.

Solo: Elleste Solo is the oestrogen-only form for women without a uterus. You should take a tablet every day and can start taking the pills at any time.

Solo MX: is a transdermal patch that you attach to your skin as a discreet alternative to the tablet version. Patches should be changed twice a week. Attach Elleste Solo MX to a clean, flat, hairless area of skin. Vary your patch site to avoid skin irritation. Elleste Solo MX patches are available as a low dose 40mg and a high 80mg version. You can start using the patch at any time.

Duet: Elleste Duet is a combined HRT tablet that should be taken each day. The 1 mg pack contains 16 white tablets and 12 pale green tablets. You should start with the white ones.

The stronger 2mg packet of Elleste Duet contains 16 orange tablets and 12 grey ones. You should start with the orange tablets.

Duet's white and orange tablets contain only oestrogen, the pale green and grey tablets contain both oestrogen and progesterone. This ensures your hormones are taken in the right order.

Elleste Duet Conti: All Elleste Duet Conti tablets are a combined HRT. All pills contain the same amount of hormones, so the order does not matter although you should take them in the direction of the printed packet arrows to ensure you don't get mixed up and take too many or miss a dose.

Elleste Duet and Elleste Duet Conti should be taken on the first day of your period if you still have them. If you have finished your menstrual cycles you can begin at any time.

Elleste Dosages

Elleste is available in two different doses to suit your needs. Women with conditions that may preclude them from Elleste or those who experience side effects should use the lowest dose available.

  • Elleste solo contains only oestrogen and is available as 1mg or a 2 mg dose
  • Elleste Solo MX is available as a 40mg or 80mg patch
  • Elleste Duet contains both oestrogen and progesterone. It's available in a 1mg dose with 1mg of oestrogen in the white tablets and then 1mg of oestrogen and 1mg of progesterone in the pale green tablets
  • The 2mg dose contains 2mg of oestrogen in the orange tablets and 2mg of oestrogen and 1 mg of progesterone in the grey tablet
  • Elleste Duet Conti contains 1mg of progesterone and 2mg of oestrogen

Elleste Side Effects

Women taking HRT should always use the lowest dose they need for the shortest time in order to avoid side effects. As well as being aware of the precautions above, users of Elleste should be aware of potential side effects.

More common side effects include:

  • Headache
  • Breast pain or breast tenderness
  • Painful periods, vaginal discharge or breakthrough bleeding
  • Feeling down, feeling anxious, mood changes or changes in sex drive
  • Feeling dizzy
  • Difficulty sleeping
  • Feeling sick, bloated, diarrhoea, indigestion or stomach cramps
  • Acne, rashes, itchiness or dry skin
  • A feeling of weakness, swelling of the ankles, feet or fingers
  • Increase in weight

These side effects may pass as you become used to the new dose of hormones, but if they persist or are intolerable speak to your doctor about changing your HRT.

Uncommon side effects include migraines, high blood pressure, varicose veins, vomiting, gallstones skin colour changes, and cramps.

Rarely women may experience extra hair growth or hair loss, skin discolouration or nodules and dry eyes. Very rarely women may experience an allergic reaction to Elleste. Do not take Elleste in any form if you have a known allergy. If you begin to take Elleste and develop difficulty breathing, hives, or a swollen throat, lips and mouth seek immediate medical help. An allergic reaction is very rarely experienced.

Elleste Precautions

No hormone replacement therapy is a contraceptive. If you are still having periods, or it been less than a year since your last period, you can still fall pregnant. Speak to your doctor about contraception. You may be advised to use barrier methods such as condoms or an intrauterine device (IUD) that uses copper to prevent pregnancy. Hormonal contraception should not be used alongside HRT unless your doctor recommends it as it increases the amount of hormones in your body and can lead to side effects.

Elleste does not protect you against sexually transmitted infections (STIs). If you are having unprotected sex and are unsure about your partner's sexual history you should use condoms to protect yourself against STIs such as chlamydia, syphilis and HIV. Your doctor or local sexual health clinic can offer screening if you think you may have an STI.

Using hormones can raise your risk of some serious conditions. These include:

  • Blood clots. It's thought that women in their 50s who have taken HRT for five years raise their risk of a blood clot by an extra five cases in 1,000 users. The risk is increased if you smoke or are overweight. Travelling long distance by air raises the risk, as does being immobile e.g. you've had an operation.
  • Oestrogen-only HRT can cause excessive thickening of the womb lining which is why Elleste Solo and Elleste Solo MX are not suitable for women with a uterus
  • The risk of breast cancer rises slightly with HRT use. The risk rate depends on how long you use HRT, but it subsides when you stop taking tablets. The risk returns to standard after a few years. You should always check your breasts because breast cancer is more common in older women whether or not they use HRT
  • There is slight rise in the risk of ovarian cancer in women taking HRT for at least five years
  • Women over the age of 60 who use combined HRT are slightly more likely to experience heart disease and their risk of a stroke may slightly rise
  • Women taking thyroid replacement will need special monitoring as HRT can reduce the level of thyroid hormone
  • There is also a slight risk that HRT may cause a higher risk of memory loss in women who begin HRT after the age of 65
Other Medication Interaction

All HRT methods are prescription medications because they can interact with other medicines and cause problems. If you take HRT you should always tell your doctor, dentist or pharmacist what you are taking, even if you are buying over-the-counter remedies.

Medicines that cause an interaction include:

  • Epilepsy medicines
  • Some antibiotics
  • Some HIV medications
  • St John's Wort
  • Medicine for diabetes

HRT may also affect laboratory tests so it's important to mention your HRT tablets if you need any medical tests.

Elleste HRT is designed for women experiencing their menopause. It is a clinically proven and highly effective form of hormone replacement, but there are some women who are not suited to it. You should not take Elleste if you have ever experienced the following conditions:

  • Breast cancer
  • Oestrogen sensitive cancers such as womb-lining cancer
  • Any unexplained vaginal bleeding
  • Untreated endometrial hyperplasia
  • A blood clot in a vein (DVT) or in the lungs
  • A blood clotting disorder
  • If you recently had a blood clot associated illness such as a heart attack, stroke, angina
  • Liver disease
  • Porphyria
  • An allergy to any of the ingredients
  • If you are pregnant, think you are pregnant or are breastfeeding
  • Elleste Solo and Elleste Solo MX in particular are designed for women who do not have their uterus

You may not be able to use Elleste if you have any of the following conditions or life choices. Speak to your doctor about any potential risks as it may be that the benefits of Elleste outweigh them.

If you have any of the following and are prescribed Elleste, it's likely you will need extra monitoring or take special precautions. The lower doses of Elleste are likely to be more suitable if you have any of these conditions.

  • Fibroids
  • Endometriosis
  • Endometrial hyperplasia
  • At increased risk of blood clots e.g. smoking or being overweight
  • A close relative with oestrogen sensitive cancer
  • High blood pressure
  • Liver disorder
  • Diabetes
  • Gallstones
  • Migraines
  • Lupus (SLE) or other autoimmune disease
  • Epilepsy
  • Asthma
  • Disease affecting the eardrum
  • High levels of fat in your blood
  • Fluid retention due to cardiac or kidney problems
  • Select

  • Fill out a short
    medical form

  • Doctor issues

  • Medication sent
    from pharmacy