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  • Pack of 84 Kliovance 1mg/0.5mg estradiol/norethisterone acetate film-coated tablets
  • Box of Kliovance 1mg/0.5mg with calendar dial pack tablets
  • Kliovance calendar dial pack tablets

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Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

How to buy Kliovance?

When buying Kliovance online, you will have had to of ordered the medication before in-person. You will then obtain a prescription essential for ordering any clinically proven medication. After this point, you can then buy online. This will include completing our quick consultation to ensure the treatment is right for you. A certified doctor reviews this and then you can order Kliovance online.

Is it safe to order online?

When ordering from a certified online pharmacy, you can be ensured that your medication is safe. If the pharmacy doesn't ask you to complete essential health and medical question, however, this is a telltale sign that the website isn't certified. The website should also display clear signs that it is registered and approved by the relevant authorities. In the UK, this includes being registered by the MHRA, GMC .

All medication will be delivered in tamper proof packaging complete with the full patient leaflet, which confirms that the medication is clinically proven and highly effective.

What is included in the price?

When ordering Kliovance online here at Medilico, this is an all-inclusive price including the prescription, consultation, medication and delivery. There are no hidden costs. This medication is only available in one dose of 1mg/500mcg and one quantity of 84 tablets.

Can you buy without a prescription?

You need a prescription in order to take Kliovance. It is not possible to buy it over-the-counter. Your doctor will examine you and decide whether Kliovance is suitable. Once you have been prescribed Kliovance by your doctor you can order it online following a consultation.

What Is Kliovance?

Kliovance is a combined form of HRT that effectively treats the symptoms of menopause including hot flashes, irregular periods, night sweats, mood swings and a dry uncomfortable vagina.

The estradiol Kliovance contains is classed as a natural oestrogen as it's the same as the type produced by your ovaries. The norethisterone acetate element is a synthetic progestagen. Progesterone is another female hormone that regulates your reproductive capacity.

Kliovance is a hormone replacement therapy (HRT) for women who have finished menstruation.

How Does Kliovance Work

It works when the two active ingredients replace those hormones that have naturally been lost through the process of menopause. As women grow older they produce less oestrogen and their fertility drops. The drop in sex hormones produces symptoms that can be hard to manage. Kliovance simply replaces sex hormones that lead to an easier menopause. Once the transition into menopause is complete you can stop taking the medication. Kliovance does not produce regular monthly periods as some HRT does.

The progestogen element in Kliovance protects against the risk of endometrial cancer. On its own oestrogen can stimulate womb lining growth. The dose of progestogen opposes the oestrogen and reduces the risk of cancer.

Kliovance can be used to reduce the risk of osteoporosis in women who have reached menopause. Oestrogen is used to build healthy, strong bones. When the body stops producing oestrogen there is a risk that your bones will lose density and be more prone to fractures. The oestrogen in Kliovance helps to strengthen and protect your bones after the menopause.

How To Take Kliovance

Kliovance is a daily treatment. You should swallow a whole tablet, without crushing or chewing it, once a day. You can do this with or without food but try to take it at the same time each day. This ensures you have a regular spacing between hormone doses.

If you forget to take Kliovance and it's less than 12 hours overdue simply take it as usual. If you are more than 12 hours overdue you will need to miss out the dose completely and take your next dose at the established time. You should never double up a dose as this can lead to unwanted side effects. If you do miss a dose you may experience some breakthrough bleeding.

There is no need to take a break from Kliovance. It is designed to be taken daily until you no longer need the treatment.

Kliovance Dosages

Kliovance is taken as a daily tablet. The tablet contains 1mg of estradiol (oestrogen) and 500 mcg of progestogen (norethisterone acetate).

Kliovance Side Effects

Kliovance is a prescription medicine and you may therefore experience some side effects. Most are mild and may wear off after a few months of use. Some women find it's worth persevering with mild side effects to gain the benefits that Kliovance provides, however if you experience unwanted side effects, they worsen or you cannot tolerate them speak to your doctor about changing to another HRT treatment.

Mild and common side effects include period pains, breast tenderness, indigestion, nausea, diarrhoea, bloating, headaches, thrush, leg cramps, abnormal hair growth, sleep disturbances and changes in sex drive.

More serious side effects that require medical assistance include:

  • Pain or swelling in the legs
  • Jaundice
  • Migraine or sudden severe headache
  • Eyesight problems
  • A rise in blood pressure
  • Breast changes

An allergic reaction to Kliovance is a medical emergency. It is very rare but if you feel short of breath, wheezy, develop a skin rash or hives, have a rapid pulse you should seek immediate medical advice.

Long term side effects linked to Kliovance and other oestrogen containing HRT can be serious. This is why regular medical reviews are necessary if you take HRT. Most women take HRT without any problems but there is raised risk of the following issues:

  • Heart Disease
  • Stroke
  • Blood Clots (deep vein thrombosis)
  • Breast cancer
  • Endometrial cancer
  • Ovarian cancer
  • Dementia

Other Medications With The Same Active Ingredient:

  • Climagest tablets
  • Climesse tablets
  • Clinorette tablets
  • Elleste duet tablets
  • Elleste duet conti tablets
  • Evorel conti patches
  • Evorel sequi patches
  • Kliofem tablets
  • Novofem tablets
  • Nuvelle continuous tablets
  • Trisequens tablets

Kliovance Precautions

If you take Kliovance or any HRT treatment it is essential that you have a medical check up at least once every year. This is to ensure that your treatment is still safe for you. If you experience any health changes you should speak to your doctor.

Kliovance is not a contraceptive. Women are considered fertile until they have reached a full year without a period. Irregular periods indicate you are still ovulating and could potentially fall pregnant. Kliovance is designed to be used a full year after ovulation has finished.

Kliovance does not protect against sexually transmitted infections. If you are having sex with a new partner or are unsure about your partner's sexual health you should use barrier contraception to avoid developing STIs such as chlamydia or syphilis. Consider an STI screening if you have had unprotected sex.

You may experience some breakthrough bleeding or spotting when you take Kliovance. If this continues beyond six months you should speak to your doctor.

Who Can and Can't Take Kliovance

Kliovance is prescribed for women who are one year past their final period. Many women are able to take Kliovance but if you are sensitive to oestrogen you should speak to your doctor about an alternative.

If you have ever experienced the following conditions you should not take Kliovance.

  • If you have or have had or have a family history of breast cancer
  • If you have, had or have a family history of endometrial cancer or other oestrogen stimulated cancers
  • If you have untreated endometrial hyperplasia
  • If you have unexplained vaginal bleeding
  • If you have or have experienced blood clots
  • If you have condition that increases the likelihood of blood clots
  • If you've had a stroke or heart attack
  • If you have angina
  • If you have liver disease
  • If you have inherited blood disorders (porphyria)
  • If you are pregnant or breastfeeding

You may not be able to use Kliovance if you smoke, have experienced benign breast lumps, have fibroids, if you take warfarin, are overweight, have severe varicose veins, have high blood pressure, diabetes, migraines, epilepsy or asthma. You may also not be able to use Kliovance or any type of HRT including oestrogen if you have lupus (SLE), a history of gallbladder disease, depression or raised levels of fat in the blood e.g. high cholesterol.

Your doctor is best placed to discuss your medical history with you and may decide that an oestrogen-based HRT is not suitable. If this is the case there are other oestrogen-free HRT treatments.

Other Medication Interactions

Some medications may interfere with the effectiveness of Kliovance. These include:

  • Epilepsy medicines
  • Some antibiotics used to treat tuberculosis
  • Medicines for HIV infections
  • Herbal remedies such as St John's Wort
  • Hepatitis C medications
  • Some types of antifungal medicines

Speak to your doctor or pharmacist about any interactions with Kliovance.

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