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Home / Stop Smoking / Champix


  • Pack of Champix 0.5mg and 1mg varenicline film-coated tablets
  • Box of Champix tablets with blister packs
  • Blister pack of Champix 0.5mg/1mg tablets with a patient information leaflet

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Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

How to buy Champix?

Champix tablets can be obtained in-person or online once you have an official prescription provided by a UK registered doctor. Valid UK prescriptions can be taken to your nearest pharmacy for collection. Alternatively, you can do this process solely online if you don't have the time, can't get an appointment or aren't able to go collect your medication in-person for whatever reason.

In the UK once you have a valid prescription slip from a medical professional, the medication you collect will be completely verified and safe for you to use. This is whether you decide to obtain it over the counter or online. When buying online, look out for the valid certification marks and ensure they are asking all the relevant questions about your condition.

You can buy Champix tablets online here at Medilico after completing a simple online consultation. This consultation will be reviewed by one of our registered doctors. Once this prescription is approved your order will be dispatched from our UK pharmacy and delivered to your allocated address via our next day delivery service.

Is it safe to order online?

When ordering from a certified online pharmacy, you can be ensured that your medication is safe. If the pharmacy doesn't ask you to complete essential health and medical question, however, this is a telltale sign that the website isn't certified. The website should also display clear signs that it is registered and approved by the relevant authorities. In the UK, this includes being registered by the MHRA, GMC .

All medication will be delivered in tamper proof packaging complete with the full patient leaflet, which confirms that the medication is clinically proven and highly effective.

What is included in the price?

When buying Champix online here at Medilico, this is an all-inclusive price including the prescription, consultation, medication and delivery. There aren't any hidden costs. The price will adjust according to the dosage and quantity you order, which can be seen below:

Can you buy without a prescription?

Champix is only available to buy online with a prescription from a doctor, and so it is illegal to buy or sell this medication on your own.

You may be able to find a seller online who claims they can either get it to you without a prescription. These offers are likely scams, and should not be trusted. If you decide to order medicine through this means, what you pay for may not exist, or it may be counterfeit medication.

Counterfeit medication is often mixed with unknown substances and can cause serious health problems if used. If you have ordered medication from one of these sites and are unsure of the quality, take it to your doctor or pharmacist for inspection and notify them of the site. If you have already used the medication and you start to feel side effects not listed here, or more extreme versions of the side effects listed, contact your doctor immediately. If you are unsure of where to pick up medication with your prescription, check with your doctor to know where they recommend getting a safe, trusted product.

What is Champix?

Champix is a medication that was created to help you end your nicotine addiction and stop smoking. It was designed to significantly ease the effects of withdrawal on the body, as well as help to complete a tobacco-free programme more effectively, and is the only smoking cessation treatment that doesn't use nicotine. This relatively new medication uses ingestible tablets that contain Varenicline, which helps to fight the need to smoke in a few ways. It does this by combining with the reward centres of the brain to decrease the effects of withdrawal, and to block nicotine that tries to make its way to these points.

Champix has been compared to Zyban, another medication used to help quit smoking. While there are some similarities between the two – especially as far as side effects are noted- there are differences as well. Zyban is usually given on a seven to twelve week trial basis, and is more effective when combined with a nicotine patch or gum. In a study between the two medications, Champix was proven to both be more effective at helping a person to quit, and to keep them from relapsing over the next year.

If you are considering using Champix, the following information can help you to understand what the medication entails. Your doctor will better help you to understand if it's a good option for your situation.

How does Champix work?

Smoking is addictive because the nicotine in tobacco binds with the reward centres of the brain. It triggers pleasure whenever you smoke and use tobacco products.

Champix works by delivering Varenicline to the brain through an ingested pill. Varenicline then connects to the same reward receptors that nicotine connects to. It only mimics nicotine, though, and doesn't actually use nicotine in its treatment. While it doesn't activate the pleasure centres quite like nicotine does, it does partially activate the reward pathway. As the brain believes it is interacting with nicotine, it also slows down the effects of withdrawal from actual tobacco as you stop using smoking productions. Your body eases into getting off of smoking so it isn't immediately shocked by the change, and you're able to more clearly move through your treatment.

In addition to helping offset withdrawal, Champix also blunts the nicotine sensors it covers. This means the actual nicotine can't connect as much or as well to the brain. This means the act of smoking becomes much less enjoyable and rewarding to the body. This reduces the desire to break from your smoke-free plan. Without having to fear relapse as much, the chance of a successful programme increases.

Unlike other medications of its type such as Zyban, which is also used as an antidepressant, Champix was created specifically for use with smoking cessation. Champix is also different from Nicotine Replacement Therapy (NRT) in that has no actual nicotine as part of its treatment. NRT treatments use patches and gums to stimulate the brain, but gradually draw back as treatment goes on, while Champix uses a chemical that mimics the process without actually putting nicotine into the body. This avoids the possibility of toxicity due to too much nicotine being present in the body at once and curbs the nicotine craving so effectively.

How to take Champix

When taking Champix tablets for the first time, you will be recommended the 12-week starter pack before requiring a refill pack. By following the below instructions your chances of quitting smoking will increase substantially:

  • Decide your quit date, and stick to it. Champix takes a few weeks to start working effectively, and so your first week of use will be increasing the dosage to meet your quit date. You don't need to stop cold turkey.
  • Your first week will be the week before you stop smoking. In this week you will take the medication and slowly increase the dosage, so that by the time you stop smoking altogether, Champix will have already started to work as intended and help reduce cravings.
  • You'll take the tablets twice daily. It's best to take the pills with a full glass of water to help it go down, and after you've eaten something.
  • The treatment will last for about 12 weeks. Usually, after these 12 weeks withdrawal symptoms will lessen.
  • Rather than stopping the medication abruptly, many Champix users decide to take an additional 12 weeks worth of medication to ensure they have quit smoking indefinitely. Your doctor will be able to offer future advice on this.

If you have felt little effect from Champix tablets in the first 12 weeks, you may be instructed to stop using the medication. If you made some changes the first 12 weeks but have not noticed a significant change after the second 12 weeks, Champix may not be useful in your case. In this case, you should talk to your doctor about what other steps you can take, such as alternative medications or therapies.

It's important to remember that all smoking cessation requires willpower and Champix is no different. In order to be successful with this medication, you need to have the desire to quit smoking for good, which can include options such as counseling and other measures to deal with other facets of nicotine craving. A doctor will likely not prescribe this medication until you have the other steps necessary in making this journey.

While Champix is a great help in quitting the habit for good, there are other parts needed to ensure that you don't relapse and quit completely. A doctor is unlikely to give you a prescription for the medication without a well-constructed programme.

As part of your smoking cessation, it is encouraged to enlist all the help available to you. This can include counseling as well as support from your friends and family. Your counselor will help you to figure out why you smoke and what you can do instead. You will also need to update your doctor regularly on how you are feeling mentally and physically, and whether the medication is working for you or not.

Champix Dosages

Usually, the dosage for Champix is 0.5 milligrams daily for the first three days, then 0.5 mg taken daily for the rest of the week. For the next 11 weeks after that, you're going to take 1mg twice daily.

Like most medication, your doctor may decide to change the dosage size. This can be due to a few factors:

  • You may take medications that will start to leave your body more slowly with Champix, as listed in the next section.
  • You may be diabetic and need to balance out your insulin needs.
  • You are on your second 12-week process.
  • You have been dealing with changes in mood or behaviour, or kidney/cardiovascular health, due to use of the medication.

If your doctor alters your medication dosage and problems arise, such as feeling like it is ineffective, let them know.

Champix Side Effects

Champix comes with a number of possible side effects, though few are serious if they even occur. If you experience any of the following in a way that makes it difficult to get through the day, talk to your doctor immediately.

The most common side effects include nausea, insomnia and abnormal dreams, headaches, vomiting, diarrhoea and gas.

Some less common, but more numerous side effects include a decreased appetite, feeling thirsty, shortness of breath, throat irritation, a runny nose, snoring, mood swings (including depression, anxiety or abnormal thinking), hallucinations, restlessness, changes in sex drive, tremors, abnormal coordination, inflammation of the nose and throat (nasopharyngitis) / sinuses (sinusitis) / lungs (bronchitis), problems with speech, a reduced sense of touch or taste, ringing in the ears (tinnitus), visual disturbances, watery eyes, skin reactions (such as rash, itching, acne or sweating), increased urination, Vomiting blood or blood in the stools, inflammation of the stomach (gastritis), chest pain or increased blood pressure.

One very rare side effect is a stroke. If you feel you are experiencing the effects of a stroke, or if any of the above side effects persist you should speak to a medical professional as soon as possible for advice.

Champix Precautions

It is important to understand that, with any smoking cessation programme, there are likely to be some changes in mood. Even with Varenicline's ability to mimic nicotine, there will still be symptoms of withdrawal. This can cause an elevation in depression, aggravation and anxiety. There is a chance that the use of this medication could lead to an increase in hostility, agitation, depressed mood, suicidal thoughts, attempted suicide and self-harm if you are prone to it. If you should feel an increase in any of these moods or behaviour, it is suggested that you call your doctor and notify them immediately and stop using the medication.

Let your doctor know about these changes, but do not worry about these changes unless they become more extreme and hard to handle.

There is a possibility that using Champix has been linked to an increase in the risk of heart problems. Various studies have alluded to (but have not definitely shown) using Champix while living with a cardiovascular disease can increase the chance of cardiovascular events such as heart attacks. While this connection is not definite, it is still suggested to notify your doctor if you have any existing heart problems or conditions first. If, while taking Champix, you notice the onset of any cardiovascular events, you are recommended to tell your doctor and get off the medication.

Finally, there is a chance that using Champix may cause dizziness or sleepiness that can interfere with the ability to drive or use heavy machinery. You are advised to not drive or operate such machinery when beginning the medication until it's understood that you are free from those side effects.

Who Can and Can't Use Champix

As far as studies have shown, most of the population can use Champix without any worry beyond the side effects. Other than what is later discussed in the Precautions section, Champix is generally mild for most people. However, there are some parts of the population that should always use caution with medications like Champix due to the possibility of adverse effects. These effects are more prevalent in younger people.

  • Those under the age of 18, who are still developing mentally and physically, are also cautioned against use of Champix.
  • Those with severe kidney conditions should use Champix with caution. There is no concrete understanding of how the medication interacts with kidney problems, and until more evidence is available, those with such conditions should go per their doctor's recommendations.
  • If you have a condition linked to a specific mental disorder, mood and behavioral problems, and heart problems. These people are at a higher chance of negative possible effects from using Champix.

These cautions are not clinical, and may not apply to you. Speak with your doctor or general practitioner for their diagnosis, and if they feel that Champix is right for you, then follow their recommendation. Let your doctor know if there are any problems from your use of the medication, or if any of the described conditions act up with the medication.

Pregnancy and breastfeeding

Champix has not been licensed for use with women who are pregnant or breastfeeding because it is unknown how the medication may affect babies. If you are a breastfeeding mother and have used other means to try and stop smoking, and none have worked, you may want to try Champix. In this case, speak with your doctor about the risks and about the dosages you can use. You may also want to stop breastfeeding for the duration of using this medication.

Other medication interactions

Due to the possibility of side effects from taking multiple medications, always let your doctor know what you are taking so that they can best inform you of any interactions that can occur.

In general, Champix has not been widely tested in combination with other similar medications. It is not specifically known whether such a combination would be effective, however, due to overlap, it is not recommended.

In some cases, mixing Champix along with nicotine replacement therapy has shown an increase in negative side effects. These include increases in nausea, headache, vomiting, dizziness, indigestion, fatigue and drops in blood pressure, more than if you used NRT by itself.

If you have severe kidney problems, do not take Champix with cimetidine, as it can increase the amount of varenicline in the blood that your kidneys have to deal with. This can lead to complications and may result in more damage or other dangerous occurrences and impairments.

The following medicines are sometimes removed from your body faster due to the chemicals in tobacco smoke. When you start to smoke less, these medicines may stay in your body longer. Due to this, your doctor may need to prescribe you a different dosage to regulate how quickly your body removes the medicine.

  • Clozapine
  • Dextropropoxyphene
  • Flecainide
  • Fluvoxamine
  • Olanzapine
  • Pentazocine
  • Phenylbutazone
  • Some benzodiazepines, e.g. oxazepam
  • Some beta-blockers, e.g. propranolol
  • Tacrine
  • Theophylline
  • Tricyclic antidepressants, such as imipramine
  • Warfarin

If you are diabetic and smoke, you likely had to take more insulin in your body because smoking reduces the amount you can absorb. If you have decided to use Champix to quit smoking, you'll need less insulin once you quit, so work with your doctor to reduce your intake to accommodate this change.

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